When we talk about cardiovascular health, everyone thinks of cholesterol. It is still important to remember that cholesterol is essential for life. Although there is what is known as good and bad cholesterol, there is only one molecule. Good cholesterol refers to HDL which are high density transporters that are effective in moving cholesterol within the human body. The bad cholesterol, LDL, are low-density transporters that, once oxidized, stick to the walls of the arteries to cause atherosclerosis (blockage of the arteries which also involves inflammatory processes).

It is now clear that the consumption of dietary cholesterol has a low impact on blood cholesterol. The vast majority of our cholesterol is produced by the liver in response to our needs for cellular health or hormone production. This is modulated according to the quality of our food. It is therefore towards our lifestyle that it is best to focus on, in order to improve the profile of our cholesterol, and above all, to prevent it from oxidizing so that it does not block our arteries. An important ally: a balanced Mediterranean-type of diet which includes olive oil.

Followers of the Mediterranean diet in Europe commonly consume very high-quality olive oil at amounts of 25-50ml of oil per day. An extensive analysis of the scientific literature led the European Union to approve a health claim for 5 mg of hydroxytyrosol and its derivatives (polyphenols from olives) per day, which corresponds to food consumption. It is precisely a claim for the reduction of the risks of cardiovascular diseases related to the blockage of the arteries by bad oxidized cholesterol (what is called atherosclerosis). It is on this health claim that we based the dose of olive polyphenols in the Provitol® Complex exclusive to Vitoli® products (also present in Vitoli® Cardiovascular).

Olive polyphenols reduce the oxidation of bad cholesterol and promote the production of good cholesterol, but that’s not all. These natural molecules would slow down aging according to a study published by European researchers (de Pablos et al., 2019).

Slow down aging

De Pablos and collaborators have reviewed all the cellular mechanisms that explain the anti-aging effects of olive polyphenols. These are effects on:

  1. Reduction of lipogenesis (the production of fat)
  2. Increased lipolysis (fat breakdown)
  3. Increased cell survival
  4. Increase in antioxidant capacities
  5. Increased DNA repair
  6. Improved mitochondrial health
  7. Epigenetic modifications with preventive effects on cancer

What is most interesting in this scientific article is that these mechanisms of action are subsequently linked to health benefits associated with prevention or aging.

The authors also presented a large number of animal studies and human clinical studies. 18 clinical studies were reported on various topics such as:

  • Osteoarthritis,
  • Cardiovascular illnesses,
  • Cholesterol problems and
  • Metabolic problems.

A very complete product

We developed Vitoli® Cardiovascular to create the best product for people who are concerned about their cardiovascular health. It does not only act on cholesterol, but on several facets at the same time.

It contains :

  • The dose recommended by the European Union of olive polyphenols (the exclusive Provitol® Complex) for the reduction of the risks of atherosclerosis related to oxidation,
  • Coenzyme Q10 and
  • Group B vitamins (B6, B9 and B12).

Claims permitted by Health Canada for Vitoli® Cardiovascular:

  • Helps maintain and support cardiovascular health.
  • Provides antioxidants for the maintenance of good health.

Some testimonials

Here are some testimonials from the Testimonials section of the Vitoli website. These are people who wrote to us to thank us and we asked them if we could use their testimony by mentioning their full name, their age and their region in order to demonstrate that they are real people:

  • I’m 81 years old. I suffered from chronic high blood pressure (between 140 and 180). I didn’t want to increase my medication. The discovery of Vitoli Cardiovascular completely changed my life. My blood pressure now hovers between 120 and 127 (systolic) and 77 and 81 (diastolic). Moreover, to my great astonishment, my general vitality has greatly increased. THANK YOU VITOLI! Jean-Paul Simard, 81 years old, Chicoutimi.
  • I started by taking Vitoli Joints which ended up solving my problem. I then wrote to Vitoli to ask if there was Vitoli for blood pressure, because my blood pressure was always high and my physician was advising me to take chemicals. They recommended Vitoli Cardiovascular. I have been taking this product for three months and my blood pressure has returned back to normal. My pressure which was always high: 150/95 decreased to 130/75. That’s wonderful! Thank you again Vitoli. Hélène Lamontagne, 69 years old, Joliette.

 

 

Other suggested readings:

 

 

References:

  • Barzilai, et al, 2012. The rationale for delaying aging and the prevention of age-related diseases. Rambam Maimonides Med J. 2012 Oct 31;3(4).
  • Bertelli M, Kiani AK, Paolacci S, et al. Hydroxytyrosol: A natural compound with promising pharmacological activities. J Biotechnol. 2020;309:29–33.
  • Cicerale et al, 2010. Biological Activities of Phenolic Compounds Present in Virgin Olive Oil. Int J Mol Sci. 2010; 11(2): 458–479.
  • de Pablos RM, Espinosa-Oliva AM, Hornedo-Ortega R, Cano M, Arguelles S. Hydroxytyrosol protects from aging process via AMPK and autophagy; a review of its effects on cancer, metabolic syndrome, osteoporosis, immune-mediated and neurodegenerative diseases. Pharmacol Res. 2019;143:58–72.
  • Eric Simard, Dr en biologie. 2016. Vivre jeune plus longtemps; Chapitre 3.2, Les polyphénols d’olives et la diète méditerranéenne. Marcel Broquet la Nouvelle édition. 364 pages.
  • Matthew J. Rossman, Jessica R. Santos-Parker, Chelsea A.C. Steward, Nina Z. Bispham, Lauren M. Cuevas, Hannah L. Rosenberg, Kayla A. Woodward, Michel Chonchol, Rachel A. Gioscia-Ryan, Michael P. Murphy, and Douglas R. Seals. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension. 2018;71:1056–1063.
  • Menendez et al, 2013. Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil. A new family of gerosuppressant agents. Cell Cycle 12:4, 555–578; February 15, 2013.
  • Nahas R. 2008. Complementary and alternative medicine approaches to blood pressure reduction: An evidence-based review. Can Fam Physician 2008 – Review.
  • Nallamothu BK, Fendrick AM, Omenn GS. Homocyst(e)ine and coronary heart disease: pharmacoeconomic support for interventions to lower hyperhomocyst(e)inaemia. 2002;20(7):429–442.
  • Peyrol et al, 2017. Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders. Review. Nutrients 2017, 9, 306.
  • Raizner AE. 2019. Coenzyme Q(10). Methodist Debakey Cardiovasc J 2019 – Review.
  • Visioli et al, 2002. Antioxidant and other biological activities of phenols from olives and olive oil. Med Res Rev. Jan;22(1):65-75. Review.